Pathogenesis of osteoarthrosis.
نویسندگان
چکیده
منابع مشابه
New knowledge of osteoarthrosis.
It is being gradually accepted that osteoarthrosis should be regarded in functional terms and, for investigative purposes, as 'joint failure'. Various anatomical, metabolic, and tissue factors can all produce the same end result in the final common pathway of cartilage degeneration, pain, and loss of joint function. Thus osteoarthrosis is a heterogeneous disease that is age-related but is not m...
متن کاملAnatomy and physiology of the mineralized tissues: role in the pathogenesis of osteoarthrosis.
Synovial joints are composed of several different kinds of tissue that interact to protect normal joint function. Three subchondral mineralized tissues can be identified-calcified cartilage, subchondral cortical bone, and subchondral trabecular bone-which are distinguished morphologically, physiologically, and mechanically. Each responds to mechanical and pharmaceutical stimuli in different way...
متن کاملMechanical factors and patellofemoral osteoarthrosis.
This paper investigates the possible role of mechanical stress in the development of the osteoarthrotic lesions frequently observed in the patellofemoral compartment of the knee joint. First the location of these destructive lesions was determined by studying the location and pattern of contact in the patellofemoral joint. The study was carried out on 39 cadaveric knees for the range of flexion...
متن کاملDrug Therapy in Knee Osteoarthrosis.
Clinical treatment for osteoarthritis (OA) is very important and is based on patient's self care and guided by the physician. Drug therapy is additional to losing weight, improving muscular strength, proprioception, flexibility and range of motion. Between the available drugs for osteoarthritis' treatment, some are basically analgesics and do not interfere on disease's progression; some are ant...
متن کاملJoint capsule collagen in osteoarthrosis.
It has long been recognized that although osteoarthrosis is characterized by degenerative changes in the articular cartilage and bones, changes in the capsule play an important part in the symptoms. The capsule becomes thickened and lacks its normal pliability, thus restricting normal movement (Gade, 1947; Apley, 1969) and resulting in pain in the joint. Similarly, Jayson (1969) described a ser...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMJ
سال: 1977
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.6097.1291-b